Autonomic Dysfunction and Spinal Cord Stimulation in Complex Regional Pain Syndrome
Sponsored by Vanderbilt University Medical Center
About this trial
Last updated 7 years ago
Study ID
071060
Status
Terminated
Type
Interventional
Phase
N/A
Placebo
No
Accepting
18 to 65 Years
All
Not accepting
Healthy Volunteers
Trial Timing
Ended 15 years ago
What is this trial about?
To demonstrate that spinal cord stimulator has an effect on sympathetic function (the one
that give us the fight and flight response). Therefore, if the spinal cord stimulator has an
effect on sympathetic function, the responses from CRPS patients to different stimuli will
differ significantly pre and post SCS implant.
If CRPS patients exhibit autonomic, CRPS patients could be stratified according to their
sympathetic function pre-implant. It is expected that patients with a moderate/mild form of
autonomic dysfunction will have better outcomes with the SCS.
What are the participation requirements?
Inclusion Criteria
- CRPS patients meeting the inclusion criteria according to the International Association for the Study of pain task Force will be included in the study.
- Age: 18 to 65.
- Disease duration of at least 6 months.
- History of unsuccessful long lasting therapies: physical therapy, transcutaneous electrical stimulation and medication.
Exclusion Criteria
- Presence of current or past pulmonary, hepatic, renal disease, arthritis, hematopoietic, and neurological diseases not related to CRPS.
- Anticoagulant therapy, cardiac pacemaker used.
- Pregnancy test for females is positive.