Personalized Transcranial Magnetic Stimulation (TMS) for Metabolic Dysfunction and Alcohol-Related Liver Disease
Sponsored by The Affiliated Hospital of Hangzhou Normal University
About this trial
Last updated 4 months ago
Study ID
Status
Type
Phase
Placebo
Accepting
Trial Timing
Started 4 months ago
What is this trial about?
What are the participation requirements?
Inclusion Criteria
* Participants are able to understand the study protocol, requirements, and restrictions, are fully informed of potential adverse events, are willing to comply with follow-up visits, and voluntarily sign the informed consent form before enrollment.
* Meet the diagnostic criteria for MASLD according to the Guidelines for the Prevention and Treatment of Metabolic (Non-Alcoholic) Fatty Liver Disease (2024 Edition), and fulfill the European definition of MetALD with moderate alcohol consumption (20-50 g/day for women; 30-60 g/day for men).
* Age between 18 and 65 years.
* Body mass index (BMI) > 24 kg/m².
* No history of alcohol abuse.
Exclusion Criteria
* Contraindications to magnetic resonance imaging (MRI) or transcranial magnetic stimulation (TMS).
* Mild cognitive impairment, defined as Montreal Cognitive Assessment (MoCA) score < 25.
* Severe comorbid somatic diseases or neurological disorders.
* History of psychiatric disorders, or current use of antipsychotic medications.
* Pregnant or breastfeeding women, or those planning pregnancy.
* Previous TMS treatment within the last 3 months.
