Volume-Restricted Resection for Perihilar Cholangiocarcinoma
Sponsored by Yongjun Chen
About this trial
Last updated 9 months ago
Study ID
TJ-IRB202507012
Status
Not yet recruiting
Type
Observational
Placebo
No
Accepting
All Ages
All Sexes
Trial Timing
Started 5 months ago
What is this trial about?
The goal of this observational study is to learn about the safety and long-term outcomes of volume-restricted liver resection in patients with perihilar cholangiocarcinoma (pCCA) who have an insufficient future liver remnant (FLR). The main question it aims to answer is:
Does volume-restricted liver resection improve surgical safety and long-term survival compared with standard treatment in pCCA patients with insufficient FLR?
Participants with insufficient FLR who undergo volume-restricted liver resection or receive non-surgical treatment as part of their routine medical care will be followed for survival, postoperative complications, and other clinical outcomes. Data from patients with sufficient FLR undergoing standard radical resection will also be collected for comparison.
What are the participation requirements?
Inclusion Criteria
* Patients with pathologically confirmed hilar cholangiocarcinoma, or those with a high index of clinical suspicion for hilar bile duct malignancy despite the lack of histological confirmation.
* Patients who are able to understand and cooperate with this study.
* Patients who are able to provide and sign the written informed consent form before undergoing any screening procedures related to the study.
Exclusion Criteria
* Patients with preoperatively or intraoperatively confirmed distant metastasis, including peritoneal dissemination, distant lymph node metastasis, hepatic or other organ metastasis.
* Patients who underwent palliative surgery only.