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A Retrospective Cohort Analysis of SMARCA4-Deficient Lung Cancer

Sponsored by Shanghai Pulmonary Hospital, Shanghai, China

About this trial

Last updated 10 months ago

Study ID

L23(357)

Status

Completed

Type

Observational

Placebo

No

Accepting

All Ages
All Sexes

Trial Timing

Ended a year ago

What is this trial about?

This is a single-center retrospective analysis to explore the clinical characteristics, therapeutic efficacy, and tumor immune microenvironment of SMARCA4-deficient advanced non-small-cell lung cancer (NSCLC).

What are the participation requirements?

Inclusion Criteria

* Diagnosed with stage III-IV NSCLC according to the American Joint Committee on Cancer staging criteria (7th edition);

* Lesions are measurable according to the Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1;

* Receiving first-line immunotherapy or chemotherapy as anti-tumor treatment.

Exclusion Criteria

* SMARCA4 gene test was not performed;

* Not receive treatment;

* Lost to follow-up after one treatment cycle.