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Cold Snare Versus Cold Forceps Polypectomy for Small Lesions

Sponsored by Azienda USL Modena

About this trial

Last updated a year ago

Study ID

04-2025

Status

Not yet recruiting

Type

Interventional

Phase

N/A

Placebo

No

Accepting

18+ Years
All Sexes

Trial Timing

Started 6 months ago

What is this trial about?

The goal of this clinical trial is to compare the efficacy and the safety of a new device for cold forceps polypectomy (CFP)- a special jumbo forceps- to cold snare polypectomy (CSP) for small colorectal lesions, without adding peri- or post-procedural risks to the patient. The main questions it aims to answer are: * Does the cold forceps guarantee a complete endoscopic resection rate? * How many adverse events could the jumbo forceps reduce in comparison to CSP? * Does the lesion retrieval rate increase? * Does the polypectomy duration decrease? Participants will be randomized to one or to the other group when a polypoid or non-polypoid lesion is identified. If multiple polyps are found in the same patient, they will be removed using the same polypectomy technique. If polypectomy cannot be performed using the indicated technique, a crossover will be done according to the best practice of care principles.

What are the participation requirements?

Inclusion Criteria

* Patients aged ≥ 18 years;

* Ability to provide informed consent;

* Presence of at least one colorectal polypoid/non-polypoid lesion < 10 mm

Exclusion Criteria

* Primary or secondary coagulopathy;

* Improper interruption of dual antiplatelet therapy and/or antiplatelet therapy with P2Y12 receptor antagonists (clopidogrel, prasugrel, ticagrelor) and/or anticoagulant therapy;

* Chronic inflammatory bowel diseases;

* Inpatients undergoing colonoscopy;

* Colonoscopy as part of regional colorectal cancer screening;

* Pregnancy or breastfeeding