European Real-World Registry for Use of the Ion Endoluminal System

* Patient is aged 18 years or older at time of consent.

* Patient is planned to undergo a lung lesion biopsy(s) and/or localization procedure(s) utilizing the Ion endoluminal system.

* Patient is willing and able to give written informed consent for clinical study participation.

* Patient is participating in an interventional research study or research study with investigational agents with an unknown safety profile that would interfere with participation in this study or study results.

* Female patient that is pregnant or breast feeding as determined by standard site practices.

* Patient is legally incapacitated or in a legal/court ordered institution or is part of a known vulnerable population, including but not limited to dependency on the sponsor, hospital or study doctor.

* Patient is not willing to comply with post-procedure study participation requirements.

* Investigator, in their professional opinion, has decided that it is in the patient's best interest to not participate in the clinical study.