Investigation of GLP1-Receptor Agonists in Men With Prostate Cancer Taking Androgen Deprivation Therapy
Sponsored by Hamilton Health Sciences Corporation
About this trial
Last updated 10 months ago
Study ID
5100
Status
Recruiting
Type
Interventional
Phase
Phase 4
Placebo
No
Accepting
18+ Years
Male
Trial Timing
Started a year ago
What is this trial about?
GAIN PC CONTROL is a study investigating Glucagon-Like Peptide-1 Receptor Agonists in men with prostate cancer who are being treated with androgen deprivation therapy.
What are the participation requirements?
Inclusion Criteria
* Have a physician diagnosis of PC
* Must be receiving or planned to receive ADT (gonadotropin releasing hormone agonist or antagonist ± androgen receptor pathway inhibitor)
* Elevated BMI
1. ≥30kg/m2 or
2. ≥27kg/m2 in the presence of at least one of hypertension, type 2 diabetes, obstructive sleep apnea or dyslipidemia
Exclusion Criteria
* Type 1 diabetes
* Taking a GLP-1 RA
* <18 years of age
* History of pancreatitis
* Personal or family history of medullary cancer of the thyroid
* Multiple endocrine neoplasia type 2