The objective of the study is to investigate the effect of interventional program in
improving the quality of life for individuals with chronic schizophrenia The design of
the study will be an interventional study - Randomized Control Trial - taking place in
the Psychiatric hospital of the Cross Lebanon. Six types of intervention will be done on
the patients such as ping-pong, sport exercise, psychoeducation program, nutrition, art
therapy and bibliotherapy. A 100 patients adhering to the inclusion and exclusion
criteria will be randomized into two groups (50 patients in the intervention group and 50
patients in the control group) - Simple Randomization. A Baseline and follow-up
assessments will take place at the beginning of the study and after three months through
using Arabic Validated Scales. The scales that be used are the following Positive and
negative symptoms scale (PANSS), to determine severity of symptoms in patients. WHO
quality of life questionnaire WHOQOL- BREF Arabic version: physical, psychological,
social and environmental and EQ-5D scale, to determine quality of life of patients. MOCA
scale to determine cognitive function, Rosenberg self-esteem questionnaire, Social
functioning questionnaire QFS and Birchwood Insight Scale.

Interventional Programs' Impact on Patients' Quality of Life and Functioning

Schizophenia Disorder

Interventional Study

Schizophrenia is considered to be one of the most disabling medical conditions in the
world. It is characterized by a typical on-set in late adolescence to early adulthood,
and a low remission rate, it is regarded as being a burden to patients' daily lives.
Since there is evidence that the Quality of Life in patients with Schizophrenia is lower
than the general population, it is believed that adhering to an interventional program
might alleviate negative symptoms and cognitive deficits, leading to an improvement in
Quality of Life.

Thus, this study will assess the impact of interventional program on improving the
overall Quality of Life in patients with schizophrenia. Also, to assess the impact of the
program on functional abilities, including occupational, social, and daily living skills,
in patients with schizophrenia.

Participants will be recruited from the Psychiatric Hospital of the Cross. Eligible
participants include individuals diagnosed with chronic schizophrenia, aged 18-65, and
have given informed consent. To ensure the integrity and validity of the study,
participants will be randomly assigned to either the intervention group or the control
group (standard care) using randomized software.

By employing this randomization technique, we aim to minimize selection bias and ensure
the comparability of the groups, thereby upholding the study's rigor and validity.

Intervention programs:

Six types of intervention will be done on the patients as follows:

  -  Psychoeducational intervention program prepared and will be applied by a
     psychologist

  -  Art therapy program will be done by a psychologist

  -  Bibliotherapy program will be done by a neuroscience person

  -  Nutrition program will be done a nutritionist

  -  Sport activity will be held by a physical trainee

  -  Ping Pong activity will be done by a ping pong trainer Data will be collected
     through direct observations, participant self-reports, and standardized assessments
     conducted by trained research staff.

BALANCE Program (Body, Art, Learning, Activities, Nutrition, Creativity, and Education)

The Effect of Interventional Programs on Quality of Life and Functioning Among Patients With Schizophrenia

The WHOQOL-BREF measure the subjects' perception of QOL in every domain and the subjects'
satisfaction with health and overall rating of QOL.

The WHOQOL-BREF is a shortened version of the WHOQOL-100, it is composed of 26 items that
uses a 5 point response scale ranging from 1 (very dissatisfied/very poor) to 5 (very
satisfied/very good). Four domains were addressed including the physical health (seven
items, Q3, Q4, Q10, Q15, Q16, Q17, Q18), psychological health (six items, Q5, Q6, Q7,
Q11, Q19, Q26), social relations (three items, Q20, Q21, Q22), and environment (eight
items, Q8, Q9, Q12, Q13, Q14, Q23, Q24, Q25).

Domain scores are scaled in a positive direction (i.e. higher scores denote higher
quality of life) with elevated score indicating higher quality of life. The mean score of
items within each domain is used to calculate the domain score. Mean scores are then
multiplied by 4 in order to make domain scores comparable with the scores used in the
WHOQOL-100.

The 5-level EQ-5D version (EQ-5D-5L) questionnaire is a globally used and multiply
validated tool to assess health-related quality of life (HRQoL). It consists of 2 pages:
the EQ-5D descriptive system and the EQ visual analogue scale (EQ VAS).

The descriptive system comprises five dimensions: mobility, self-care, usual activities,
pain/discomfort and anxiety/depression. Each dimension has 5 levels: no problems, slight
problems, moderate problems, severe problems and extreme problems. The EQ VAS records the
patient's self-rated health on a vertical visual analogue scale where the endpoints are
labelled 'The best health you can imagine' and 'The worst health you can imagine'.

Family medicine specialist

Global Assessment of Functioning (GAF) is a scoring system used to assess the severity of
illness in psychiatry. It measures how much a person's symptoms affect their day-to-day
life on a scale of 0 to 100. It is a numeric scale (0 through 100) used by mental health
professionals and physicians to subjectively rate the social, occupational, and
psychological functioning of adults. The highest ratings are 91-100, "Superior
functioning in a wide range of activities and the lowest ratings (besides a 0, for
"Inadequate information") are 1-10, "Persistent danger of severely hurting self or
others...OR persistent inability to maintain minimal personal hygiene OR serious suicidal
act with clear expectation of death.

Questionnaire du focntionnement sociale (QFS) It is a brief self-assessment questionnaire
made up of 16 questions covering the general functioning in the last 15 days. Eight
questions assess the frequency of social behaviors, and the eight other questions focus
on satisfaction that is withdrawn from these behaviors. The QFS makes it possible to
calculate three main indices: a "Frequency" index, a "Satisfaction" index and a "Global"
index, which corresponds to the sum of the two previous ones. The "Frequency" and
"Satisfaction" index scores range from 8 to 40 while the "Overall" index score ranges
from 16 to 80. A higher score corresponds to a better level of functioning.

Participants will be randomly assigned to the intervention group

Six types of intervention will be done on the patients as follows:

  -  Psychoeducational intervention program prepared and will be applied by a
     psychologist

  -  Art therapy program will be done by a psychologist

  -  Bibliotherapy program will be done by a neuroscience person

  -  Nutrition program will be done a nutritionist

  -  Sport activity will be held by a physical trainee

  -  Ping Pong activity will be done by a ping pong trainer

This group will follow the standard care provided by the hospital without any type of
intervention

Interventional Programs' Impact on Patients' Quality of Life and Functioning

About this trial

Study ID

Status

Type

Phase

Placebo

Accepting

Not accepting

Trial Timing

What is this trial about?

What are the participation requirements?

Locations

Location

Status