Long-term Safety Study of BHV-7000 in Participants With Major Depressive Disorder (MDD)

Key Inclusion Criteria:

1. Eligible participants must have successfully completed the Treatment/Randomization
Phase of parent studies.

2. WOCBP must have a negative urine pregnancy test at Baseline Visit.

3. WOCBP must not be breastfeeding or lactating at Baseline Visit or at any point
during the study.

Key Exclusion Criteria:

1. Any medical condition, based on the judgement of the Investigator, that would
confound the ability to adequately assess safety and efficacy outcome measures.

2. Participant non-compliance with study procedures, study drug or visit attendance in
the parent study that the Investigator deems as clinically significant or
unacceptable risk potential for this study.

3. Investigator deems participant at imminent risk of danger to others.