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Orthognathic Surgery

Effect of Mannitol on Recovery Pattern After Orthognathic Surgery

Sponsored by National Cancer Institute, Egypt

About this trial

Last updated 10 months ago

Study ID

RC1-3-2024

Status

Active, not recruiting

Type

Interventional

Phase

N/A

Placebo

No

Accepting

18-75 Years
18 to 65 Years
All
All

Not accepting

Not accepting
Healthy Volunteers

Trial Timing

Ended 10 months ago

What is this trial about?

The aim of this study is to test, whether mannitol infusion in different doses will affect recovery pattern? the investigators hypothesized that infusion of mannitol in doses of 0.5 gm/kg before recovery from anesthesia after orthognathic surgery shortens patients' recovery time, and improves recovery quality, as well as postoperative cognitive function better.

What are the participation requirements?

Yes

Inclusion Criteria

- Age: 18-65 years

- ASA status I and II patient.

- No contraindication to use of mannitol.

No

Exclusion Criteria

- ASA III and IV status

- Extreme of age: paediatric and geriatric patients

- Severe cardio respiratory, rheumatological or endocrinal disorders

- Pregnancy and lactation

- Contraindications to the use of mannitol, e.g. serum osmolality > 330, renal failure systemic hypertension, proved intra-cranial brain haemorrhage or sub-dural haematoma and hypotension.