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Obesity, Childhood
+7

Early Genetic Identification of Obesity

Sponsored by Rolfs Consulting und Verwaltungs-GmbH (RCV)

About this trial

Last updated 7 months ago

Study ID

WEGIO 01-2023

Status

Recruiting

Type

Observational

Placebo

No

Accepting

18-75 Years
2+ Years
All
All

Trial Timing

Started a year ago

What is this trial about?

TITLE: Whole genetic approach in Early Genetic Identification of Obesity (WEGIO) DESIGN: Multicenter epidemiological study STUDY POPULATION: Participants at risk for a syndromic or a monogenic genetic obesity, incl. participants clinically diagnosed with Bardet-Biedl-Syndrome (BBS) NUMBER OF PARTICIPANTS: 1000 for initial genetic sequencing and app. 40 for the follow-up documentation COORDINATING INVESTIGATOR: Prof. Dr. Arndt Rolfs

What are the participation requirements?

Yes

Inclusion Criteria

- Informed consent is obtained from the participant/parent/legal guardian - The participant is 2 years of age or older For a participant between 2 and 18 years of age: - The participant has and had a body weight more than 97th percentile before the age of 6 - The participant has one or more of the following symptoms: rod/cone dystrophy, renal abnormalities, ataxia, syndactyly, polydactyly, brachydactyly, hyperphagia, cognitive impairment, speech delay, hypogonadism For a participant who is 18 years of age or older: - The participant has BMI ≥ 30 kg/m2 - The participant had a body weight more than 97th percentile before the age of 6 years - The participant has rod/cone dystrophy - The participant is 2 or more years of age, is clinically diagnosed with Bardet-Biedl-Syndrome (BBS) or is a sibling of an individual diagnosed with BBS via the WEGIO study

No

Exclusion Criteria

- Not fulfilling the inclusion criteria