Outcome of Moderate Severity in OPC Poisoning Patients When Treated With Pralidoxime
Sponsored by Sir Salimullah Medical College Mitford Hospital
About this trial
Last updated 2 years ago
Study ID
59.18.1100.031.18.011.22.2268
Status
Completed
Type
Interventional
Phase
Phase 2
Placebo
No
Accepting
12+ Years
All Sexes
Trial Timing
Ended 3 years ago
What is this trial about?
This open level randomized controlled trial will be conducted in the department of medicine at Sir Salimullah Medical College and Mitford Hospital. Clinical severity will be assessed by the POP (Peradeniya Organophosphorus Poisoning) scale of admitted patients having a history of organophosphorus poisoning within 24 hours with clinical features and physical evidence of poisoning consumed. Only moderate severity (POP Scale score 4-7) of OPC (Organophosphorus compound) patients will be included in this study. Then one group of patients will be treated with atropine and pralidoxime and another group will be treated with atropine. The outcome will be noted as clinical improvement or recovery. hospital stay, requirement of ICU, death.
What are the participation requirements?
Inclusion Criteria
1. Patient having history of organophosphorus poisoning within 24 hours with features of moderate severity. (POP scale score 4-7)
2. Age above 12 years
Exclusion Criteria
1. Mixed poisons along with organophosphorus compound,
2. Patients with known case chronic diseases such as chronic lung disease, chronic kidney disease, Heart failure, malignancy, chronic liver disease