The goal of this registry is to collect data on patients referred for clinically
indicated coronary vasomotor function test (CFT) and answer different questions on
prevalence, safety and outcomes. The registry is observational. Patients receive yearly
online questionnaires on their anginal complaints for 5 years after their CFT.

The NetherLands Registry of Invasive Coronary Vasomotor Function Testing (NL-CFT)

Coronary Vasospasm

Coronary Microvascular Dysfunction

Non-Obstructive Coronary Atherosclerosis

Coronary Function Test

Patient questionnaires

Can be handled as dichotomous outcome with normal vs abnormal coronary function test
(CFT) results. Alternatively, can also be handled as categorical outcome with the
following categories.

  1. Normal CFT results

  2. Vasospastic endotype (epicardial or microvascular); tested by acetylcholine
     provocation

  3. Microvascular dysfunction endotype (decreased coronary flow reserve or increased
     index of microvascular resistance); tested by bolus thermodilution, optionallly with
     additional continuous thermodilution method

  4. Mixed endotype

Measured by Seattle Angina Questionnaire summary score, 0-100 with higher scores
indicating better (functional) status.

Measured by Short Form 36, 0-100 with higher scores indicating better quality of life

Collection of data on anginal complaints, use of medication and major adverse cardiac
events (MACE) by means of online patient questionnaires

Comparison of patient reported outcomes of different endotype groups Collection of data
on anginal complaints, use of medication and MACE by means of online patient
questionnaires

RadboudUMC

Amsterdam UMC

The NetherLands Registry of Invasive Coronary Vasomotor Function Testing (NL-CFT)

About this trial

Study ID

Status

Type

Placebo

Accepting

Not accepting

Trial Timing

What is this trial about?

What are the participation requirements?

Locations

Location

Status