This project will assess the effect of Huel powdered food on the satiety of 40 generally
      healthy volunteers compared to a standard breakfast of cornflakes and milk.

      To achieve this, we will recruit 40 (non-smoking) generally healthy volunteers to attend the
      study centre on two separate occasions. On each occasion they will arrive at the study centre
      fasted and will be given their breakfast of either Huel or Cornflakes and milk, matched for
      calorie content.

      The aim is to identify the size and duration of any effect on satiety of the two meals.

The Effect of Huel Powder on Appetite

Hunger

This project will assess the effect of Huel Food replacement on the satiety of 40 generally
      healthy volunteers compared to a standard breakfast of cornflakes and milk.

      To achieve this, we will recruit 40 (non-smoking) generally healthy volunteers to attend the
      study centre on two separate occasions. On each occasion they will arrive at the study centre
      fasted and will be given their breakfast of either Huel or Cornflakes and milk, matched for
      calorie content.

      We will ask volunteers to come to the research facility in Newcastle University, before they
      have had any breakfast, on two separate occasions. The volunteers must not eat or drink
      anything (except water) after 8 pm the evening before they come in. This includes not
      drinking any alcohol, tea, or coffee.

      BMI, weight, and body composition (measured via electrical impedance) will also be taken at
      the initial visit to ensure they meet the inclusion criteria

      All volunteers will be asked to complete screening questionnaires focusing on morning eating
      and exercise routine and the 'three factor eating' questionnaire before or during their
      screening visit.

      A subset of volunteers (eight in total) will be recruited to collected blood samples
      throughout the two study visits. These volunteers will go through the same screening process
      but will also have their veins assessed for cannulation suitability.

      During the two study visits, both sets of volunteers will be asked to complete appetite
      questionnaires every 15 minutes for the first hour and every 30 minutes for the remaining 3
      hours.

      Volunteers who have consented to provide blood samples will be asked to give samples just
      before they complete the appetite questionnaires.

      The blood samples will be assessed for Ghrelin, CCK, PYY, Glucose, and Insulin.

      All researchers are trained in GCP, phlebotomy and cannulation.

Huel Powder

Concentration of Peptide YY in plasma (pg/ml)

Concentration of Ghrelin in plasma (pg/ml)

Concentration of Cholecystokinin in plasma (pg/ml)

Concentration of glucose in plasma (mmol/l)

Concentration of Insulin in plasma (pmol/l)

This arm of the study will receive Huel as their first study meal with cornflakes and milk as their second

This arm of the study will receive cornflakes and milk as their first study meal with Huel as their second

The Effect of Huel Powder on Appetite

About this trial

Study ID

Status

Type

Phase

Placebo

Accepting

Trial Timing

What is this trial about?

What are the participation requirements?