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A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of IMG-007 in Adult Alopecia Areata Participants

Sponsored by Inmagene LLC

About this trial

Last updated 2 years ago

Study ID

IMG-007-202

Status

Recruiting

Type

Interventional

Phase

Phase 1/Phase 2

Placebo

No

Accepting

18-75 Years
18 to 65 Years
All
All

Not accepting

Not accepting
Healthy Volunteers

Trial Timing

Ended 8 months ago

What is this trial about?

The primary objective of the study is to evaluate the safety of IMG-007 in adults with Alopecia Areata.

What are the Participation Requirements?

Key Inclusion Criteria:

- Male or female aged ≥ 18 and ≤ 65 years

- AA with current episode of hair loss of > 6 months but < 8 years

- AA with ≥ 50% scalp involvement as defined as SALT score ≥ 50

Key Exclusion Criteria:

- Known hepatitis B, hepatitis C, or human immunodeficiency virus infection

- Evidence of active or latent tuberculosis (TB)

- History of untreated or inadequately treated TB infection.

- Active infection requiring treatment with systemic antibiotics, antivirals,
antifungals, antiparasitics or antiprotozoals at the Screening visit

- Concurrent hair loss due to other etiologies

- Primary "diffuse" type of AA

- Active inflammatory diseases on the scalp that would interfere with the assessment of
AA

- History or presence of hair transplants or micropigmentation of the scalp

- Active systemic diseases that may cause hair loss

- Other conditions or laboratory abnormality that could increase the risk associated
with study participation or could interfere with the interpretation of study results
and, in the judgment of the investigator, would make the patient inappropriate for
entry into the study.

Locations

Location

Status

Recruiting
Recruiting
Not yet recruiting
Not yet recruiting
Not yet recruiting
Not yet recruiting
Not yet recruiting
Not yet recruiting
Not yet recruiting