A Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of IMG-007 in Adults With Atopic Dermatitis (AD)

Key Inclusion Criteria:

- Male or female aged ≥ 18 and < 75 years.

- Moderate-to-severe AD.

- Documented history of inadequate response or lack of tolerability to a stable regimen
of one or more topical treatment before the Screening visit, or for whom topical
treatments are otherwise inadvisable.

- Female participants who are not pregnant or breastfeeding and meet at least one of the
following conditions: not of childbearing potential or of childbearing potential and
agrees to use a highly effective method of contraception.

Key Exclusion Criteria:

- Known hepatitis B, hepatitis C, or human immunodeficiency virus infection.

- Evidence of active or latent tuberculosis (TB).

- History of untreated or inadequately treated TB infection.

- Active infection requiring treatment with systemic antibiotics, antivirals,
antifungals, antiparasitics or antiprotozoals at the Screening visit.

- Active unstable pruritic skin conditions in addition to AD that would interfere with
the assessment of AD based on the investigator's clinical judgement.

- Other conditions or laboratory abnormality that could increase the risk associated
with study participation or could interfere with the interpretation of study results
and, in the judgment of the investigator, would make the patient inappropriate for
entry into the study.