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Small Bowel Obstruction

A Study of Intravenous Acetaminophen for Small Bowel Obstruction

Sponsored by Mayo Clinic

About this trial

Last updated 2 years ago

Study ID

23-000547

Status

Enrolling by invitation

Type

Interventional

Phase

Phase 4

Placebo

No

Accepting

18-75 Years
18+ Years
All
All

Not accepting

Not accepting
Healthy Volunteers

Trial Timing

Ended 2 years ago

What is this trial about?

The purpose of this study is to compare IV Acetaminophen for pain control to the usual care with opioids in patients admitted for small bowel obstruction.

What are the participation requirements?

Yes

Inclusion Criteria

- Small bowel obstruction diagnosed by radiographic study; and

- Abdominal pain on admission.

- Nothing per mouth diet.

- The ability to give appropriate consent or have an appropriate representative available to do so.

No

Exclusion Criteria

- Known liver failure or cirrhosis.

- Acetaminophen toxicity on admission.

- Known acetaminophen allergy.

- Alcohol intoxication on admission.

- History of substance abuse.

- Creatinine clearance < 30 (or Creatinine level > 2).

- Liver transplant recipients.

- Ileus on admission.

- Admitted for surgical intervention for SBO.

- Admitted for venting Gastric tube placement.

- On chronic opioid therapy (defined as use of opioid on daily or near daily basis within previous 45 days (both long acting and short acting).

- Presentation without abdominal pain on admission.

- Already hospitalized for other reasons and develop SBO while at the hospital.

- Pregnant women.

- Unable to provide informed consent.

Locations

Location

Status