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A Research Study of a New Medicine NNC0519-0130 in Japanese and Non-Japanese Men

Sponsored by Novo Nordisk A/S

About this trial

Last updated 2 years ago

Study ID

NN9541-4921

Status

Recruiting

Type

Interventional

Phase

Phase 1

Placebo

Yes

Accepting

18-75 Years
18 to 55 Years
Male
Male

Trial Timing

Ended 2 years ago

What is this trial about?

NNC0519-0130 is a new medicine which may possibly help participants with type 2 diabetes. This study, will look into how safe the new medicine NNC0519-0130 is, and we will measure its concentrations in the blood and look at its effects. This study will last for a maximum of 22 weeks and Japanese and Non-Japanese male participants will be included.

What are the participation requirements?

Yes

Inclusion Criteria

- Body mass index (BMI) between 23.0 kilogram per meter square (kg/m^2) and 39.9 kg/m^2 (both inclusive) at screening with a minimum weight of 50 kilogram (kg). Overweight should be due to excess adipose tissue, as judged by the investigator.

- Considered eligible based on the medical history, physical examination, and the results of vital signs, electrocardiogram (ECG) and clinical laboratory tests performed during the screening visit, as judged by the investigator.

- For Japanese participants: Both parents of Japanese descent.

- For non-Japanese participants: Both parents of Caucasian descent.

No

Exclusion Criteria

- Any disorder, which in the investigator's opinion might jeopardise participant's safety or compliance with the protocol.

- Presence or history of any clinically relevant respiratory, metabolic, renal, hepatic, cardiovascular, gastrointestinal, or endocrinological conditions.

- Glycosylated haemglobin (HbA1c) greater than or equal to 6.5 percent (48 millimoles per mole [mmol/mol]) at screening.

- Use of prescription medicinal products or non-prescription drugs, except routine vitamins, occasional use of paracetamol, ibuprofen, acetylsalicylic acid (ASA), and domperidon, or topical medication not reaching systemic circulation, within 14 days before screening.

Locations

Location

Status

Recruiting