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Nutrition, Healthy

Effects of the Consumption of SEAweed Biomass Versus PROtein Isolates on Postprandial Satiety and Metabolism

Sponsored by Singapore Institute of Food and Biotechnology Innovation

About this trial

Last updated 2 years ago

Study ID

2022/00909

Status

Active, not recruiting

Type

Interventional

Phase

N/A

Placebo

No

Accepting

18-75 Years
21 to 50 Years
Male
Male

Trial Timing

Ended a year ago

What is this trial about?

There is a need to identify alternative sources of protein that can be introduced into diets to effectively meet the protein requirements of the population. Seaweed presents a potential source of sustainable, alternative protein. In order to determine their utility in future foods, in this study we will undertake an acute postprandial trial to explore whether a macroalgae (porphyra) and a microalgae (chlorella) protein isolates are more beneficial for acute metabolic health as compared to their respective whole biomasses. In particular, we will compare the effects of whole biomasses and their protein isolates on acute glucose homeostasis, amino acid availability as well as on satiety and gut hormones.

What are the participation requirements?

Yes

Inclusion Criteria

- Male

- Chinese ethnicity

- Aged 21 to 50 years

- Able to give informed consent

- Body Mass Index (BMI) of 18.5 to 25.0 kg/m2

No

Exclusion Criteria

- Diabetic (HbA1C ≥ 6.5%)

- Smoking

- Having a dislike towards seaweed- or soy-based products

- Having allergies or intolerances to any common food ingredients including seaweed, soy, eggs, seafood, fish, milk, peanuts, tree nuts, wheat, gluten, cereal, fruits, dairy products, meat, vegetables, sugar, sweeteners, natural food colourings or flavourings, etc.

- Following special diets or having intentional dietary restrictions (e.g, vegetarians/vegans)

- Not willing to adhere to diet modification as in the study protocol

- Taking part in strenuous physical activities

- Not willing to stop any strenuous activity during or within 24 hours of study days (for those actively participating in sports at the competitive and/or endurance levels)

- Having glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency)

- Having alcohol consumption on > 4 days per week with ≥ 6 alcoholic drinks per week

- Having sustained elevation of blood pressure (≥140/90 mm Hg)

- Having previously undergone any gastrointestinal surgery or having history of gastrointestinal disorders

- Having a history of heart, liver, kidney, blood disorders (e.g., thalassemia) or thyroid dysfunctions

- Having history of tuberculosis, HIV, Hepatitis B or Hepatitis C infections

- Having any prescription medication or any other alternative medicines or supplements which may interfere with study measurements in the opinion of the study investigators

- Having donated blood within 4 weeks of study participation

- Having poor veins or having history of severe vasovagal syncope (blackouts or fainting) from blood draws

Locations

Location

Status