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Do Patients With Fish or Shellfish Allergy Tolerate the Consumption of Fish Oil Supplements? A Clinical Study

Sponsored by University Hospital, Gentofte, Copenhagen

About this trial

Last updated 2 years ago

Study ID

H-22056640

Status

Completed

Type

Interventional

Phase

N/A

Placebo

No

Accepting

18-75 Years
18+ Years
All
All

Not accepting

Not accepting
Healthy Volunteers

Trial Timing

Ended 2 years ago

What is this trial about?

The purpose of this clinical study is to test whether patients with fish or shellfish allergy can ingest different types of fish oil supplements without having an allergic reaction. To achieve this, the recruited participants will be asked to: - provide a blood sample (used for Basophil Histamine Release Assay) - undergo a skin-prick-test - partake in multiple oral provocations These three tests will indicate the likelihood that the participants can consume fish oil supplements without adverse allergic reactions (See the detailed description for an explanation of the tests). The investigators will test the participants tolerance for three different types fish oil supplements: Fish oil, Cod liver oil, and krill oil.

What are the participation requirements?

Yes

Inclusion Criteria

- Adult (≥18 years old)

- Legally competent

- Understands Danish

No

Exclusion Criteria

- Current use of antihistamine, immunosuppressants, and/or anti-IgE-treatment that cannot be safely terminated during the study period

- The presence of severe diseases such as: Cardiovascular disease, asthma, cancer, liver disease, kidney disease, hematological diseases, neurological diseases, dementia, immunological diseases, and endocrine diseases

- Chronic urticaria

- Severe atopic eczema

- Pregnancy and/or breastfeeding

- Participation in another clinical study the previous three months

- Known excessive use of alcohol and/or substance abuse

Locations

Location

Status