Brain Enhancement Training Towards Elders Resilience to Aging, Phase IIB
Sponsored by Posit Science Corporation
About this trial
Last updated a year ago
Study ID
Status
Type
Phase
Placebo
Accepting
Trial Timing
Started 2 years ago
What is this trial about?
What are the participation requirements?
Inclusion Criteria
- Participant must be 70 years of age or older
- Participant must be a fluent English speaker
- Participant must have adequate sensorimotor capacity to perform the program, including visual capacity adequate to read from a computer screen at a normal viewing distance, auditory capacity adequate to understand normal speech, and motor capacity adequate to control a computer mouse
- Participant must not have evidence of dementia as indicated by the Montreal Cognitive Assessment (MoCA)
Exclusion Criteria
- Participant with any medical illnesses, injuries or conditions predisposing to imminent functional and/or cognitive decline
- Participant requiring caregiver assistance in dressing/personal hygiene
- Participant with severe visual deficits (including visual neglect, partial field cuts, anopias) and/or severe hearing deficit that would prevent use of the computerized treatment program
- Participant with recent participation of computer-delivered cognitive training within 2 years of consent
- Participant with claustrophobia or any other contraindication to MRI scanning
- Participant with inability to complete a 1-hour MRI
- Pregnant women
- Participant with any implanted devices above the waist (e.g., cardiac pacemaker or auto-defibrillators, neural pacemaker, aneurysm clips, cochlear implant, metallic bodies in the eye or central nervous system, any form of wires or metal devices that may concentrate radio frequency fields)
- Participants with active suicidal ideation with specific plan and intent or suicide-related behaviors within 2 months of consent as measured by the Columbia-Suicide Severity Rating Scale (C-SSRS)