About this trial
Last updated 2 years ago
Study ID
N3790-W
Status
Recruiting
Type
Interventional
Phase
N/A
Placebo
No
Accepting
35 to 80 Years
All
Not accepting
Healthy Volunteers
Trial Timing
Started 2 years ago
What is this trial about?
This experimental trial is investigating the use of magnetic stimulation of the brain as a
possible treatment for people with post-stroke fatigue. Fatigue is a common condition after a
stroke and can negatively impact an individual's ability to perform desired social and
physical activities. Magnetic stimulation of the brain has been shown to improve signs and
symptoms of related psychological (e.g., depression) conditions. Participants in this trial
will receive a type of magnetic stimulation called repetitive magnetic stimulation, or rTMS.
The investigators will measure feelings of fatigue, and other clinical characteristics
related to mood and cognition, before and after participants receive rTMS.
What are the participation requirements?
Inclusion Criteria
- 35 - 80 years of age
- more than 6 months post-stroke
- able to walk 10m unassisted
- Clinically present fatigue
Exclusion Criteria
- Contraindications to MRI/TMS/rTMS (e.g. implanted metal within the head, history of seizures)
- Inability to follow simple three-step instructions
- Multiple strokes on opposite hemispheres
- Cerebellar and/or brainstem strokes
- Diagnosed comorbid neurological conditions (e.g. multiple sclerosis, Parkinson's disease, moderate/severe TBI)
- Comorbid psychological conditions (e.g. depression, anxiety, PTSD)
- strokes within stimulation sites
- Pregnancy
- Severe hypertension (resting SBP > 200, DBP > 120)
Locations
Location
Status
Recruiting