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Elbow Heterotopic Ossifications Associated With Radial Head Prosthesis

Sponsored by Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

About this trial

Last updated 2 years ago

Study ID

IIBSP-RAD-2022-52

Status

Recruiting

Type

Observational

Placebo

No

Accepting

18-75 Years
18 to 85 Years
All
All

Trial Timing

Ended a year ago

What is this trial about?

Elbow heterotopic ossification (EHO) is described as the formation of ectopic bone in tissues not supposed to around elbow. The EHO physiopathology, yet not clarified, has been suggested to be a multifactorial process in which immune system, inflammatory response, CNS and tissue expressed proteins after severe trauma boost hyperactive metabolically bone with no periosteal layer. Consistent with that, EHO has been widely related to elbow trauma, including bone, ligament, muscle or joint; iatrogenic trauma, including epicondylectomy or elbow arthroplasty; neural injuries or burns. Clinical manifestations of EHO has been reported as limited range of motion (ROM), muscle, nerve or joint pain, stiffness and ankylosis all of them leading to upper extremity disfucntion. Prevalence of EHO can range from 3%-45% depending on degree of elbow injury. To our knowledge, prevalence of EHO among radial head fractures had not been assessed previously.

What are the participation requirements?

Yes

Inclusion Criteria

- Adults between 18-85 years-old

- Comminuted radial head fractures treated with radial head arthroplasty

No

Exclusion Criteria

- Younger than 18 years; Older than 85 years

- History of previous elbow injuries or operations.

- Pathologic fractures

- Infections

Locations

Location

Status

Recruiting
Recruiting