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Extension Study to Assess Batoclimab in Participants With Thyroid Eye Disease

Sponsored by Immunovant Sciences GmbH

About this trial

Last updated 2 years ago

Study ID

IMVT-1401-3203

Status

Not yet recruiting

Type

Interventional

Phase

Phase 3

Placebo

No

Accepting

18-75 Years
18+ Years
All
All

Not accepting

Not accepting
Healthy Volunteers

Trial Timing

Ended 14 days ago

What is this trial about?

This is a 2-cohort (observational and treatment cohort) extension study for participants completing feeder studies (IMVT-1401-3201 or IMVT-1401-3202). The observational cohort will assess the durability of proptosis response of feeder studies off treatment. The treatment cohort will evaluate the efficacy of batoclimab as assessed by proptosis responder rate.

What are the participation requirements?

Yes

Inclusion Criteria

1. Have completed the Week 24 visit of the feeder study. For participants assigned to the Open-label Treatment Cohort:

1. Do not require immediate surgical intervention and is not planning corrective surgery/irradiation or medical therapy for TED during the course of the study.
2. Did not permanently discontinue batoclimab Additional inclusion criteria are defined in the protocol.
No

Exclusion Criteria

1. In the Investigator's judgement, the benefits of entry in the study do not outweigh the risk.