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Prospective Study for Neuromelanin Image Analysis

Sponsored by Heuron Inc.

About this trial

Last updated 3 years ago

Study ID

qMT-PD-02

Status

Unknown status

Type

Interventional

Phase

N/A

Placebo

No

Accepting

18-75 Years
19+ Years
All
All

Trial Timing

Ended 2 years ago

What is this trial about?

In order to develop an image analysis system that automatically detects and quantifies neuromelanin, this study aims to construct a database of a wide sample by collecting brain MRI neuromelanin images prospectively.

What are the Participation Requirements?

Parkinsin group

Inclusion Criteria:

- Adults over 19 years old

- Those who have clinically shown Parkinson's symptoms such as tremor, Rigidity,
Bradykinesa and gait disturbance and are scheduled to take MRI scans

- Dopamine transporter imaging shows a significant decrease in visual dopamine intake

- A person who can read and understand the description and informed consent form

- Upon hearing and fully understanding the detailed explanation of this clinical
trial, a person who has voluntarily decided to participate and agreed in writing to
comply with the precautions

Exclusion Criteria:

- Patient with a history of claustrophobia and mental illness;

- Patient with metallic substances in the body

- Any female subject who is likely to be pregnant who does not agree to contraception
in a medically permitted manner during this clinical trial period

- Pregnant or lactating women

- Other cases where the investigator judged that it is difficult to participate in the
study;

Healthy volunteer group

Inclusion Criteria:

- Adults over 19 years old

- A person who has no family history or diagnostic history of movement disorders;

- A person with a score of 8 or higher on the CCSIT(cross cultural smell
identification test)

- A person with a score of 27 or higher on the MMSE Test

- No Parkinson's symptoms on a neurological examination

- Upon hearing and fully understanding the detailed explanation of this clinical
trial, a person who has voluntarily decided to participate and agreed in writing to
comply with the precautions

Exclusion Criteria:

- Patient with a history of central nervous system disease or cognitive disorder

- Patient with a history of claustrophobia and mental illness;

- Patient with metallic substances in the body

- Any female subject who is likely to be pregnant who does not agree to contraception
in a medically permitted manner during this clinical trial period

- Pregnant or lactating women

- Other cases where the investigator judged that it is difficult to participate in the
study;

Locations

Location

Status

Recruiting
Not yet recruiting
Not yet recruiting