Clinical and Microbiologic Outcomes of Adjunctive Antimicrobial Photodynamic Therapy in the Non-surgical and Surgical Treatment of Teeth With Periodontal Disease
Sponsored by The University of Texas Health Science Center, Houston
About this trial
Last updated 3 years ago
Study ID
HSC-DB-21-0998
Status
Recruiting
Type
Interventional
Phase
N/A
Placebo
No
Accepting
18+ Years
All
Not accepting
Healthy Volunteers
Trial Timing
Ended a year ago
What is this trial about?
The purpose of this study is to compare clinical outcomes after mechanical debridement of at
sites exhibiting plaque induced inflammation with or without adjunctive Antimicrobial
photodynamic therapy (aPDT) and to assess the the microbiologic profile before and after
treatment with or without aPDT
What are the participation requirements?
Inclusion Criteria
- One pocket on each side of the mouth (split design)
- Single rooted tooth
- Pocket depths measured greater than 4mm with bleeding on probing
- Horizontal bone loss
- No furcation involvement
Exclusion Criteria
- current heavy smokers (>10 cigarettes/day)
- have uncontrolled diabetes (HbA1c ≥ 6.5%)
- other uncontrolled systemic diseases that may comprise healing, such as Vitamin C deficiency, any neutrophil deficiencies, immunodeficiency syndromes, or leukemia
- taking antibiotics within 3 months before the procedure
- vertical bone defects that requires surgical regenerative treatment.
- Pregnancy
Locations
Location
Status
Recruiting