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White Spot Lesions Prevention During Orthodontic Fixed Appliance Treatment: a Randomized Clinical Trial

Sponsored by University of Baghdad

About this trial

Last updated 4 years ago

Study ID

calcium fluoride nanoparticles

Status

Unknown status

Type

Interventional

Phase

Phase 3

Placebo

No

Accepting

18-75 Years
All
All
All

Not accepting

Not accepting
Healthy Volunteers

Trial Timing

Ended 3 years ago

What is this trial about?

The aim of this study is to evaluate the effectiveness of calcium fluoride nanoparticles containing orthodontic primer in preventing or decreasing the incidence WSLs over a period of 6 months in patients with fixed orthodontic appliances. This study proposed to be double blinded, split mouth, randomized clinical trial, with equal randomization (1:1 allocation ratio).

What are the participation requirements?

Yes

Inclusion Criteria

- Patients have

1. Fully erupted permanent teeth (regardless the third molar),
2. Indication to have orthodontic treatment without extraction
3. Fair or good oral hygiene before or after oral hygiene instruction
No

Exclusion Criteria

- Patients will be excluded if they had

1. Previous orthodontic treatment or extractions
2. Missing teeth
3. Active enamel caries determined by clinical examination
4. Patients with enamel hypoplasia, dental fluorosis or tetracycline pigmentation
5. Labial restorations
6. Severe periodontal diseases determined according to PDI index by Sigurd P. Ramfjord (Ramfjord, 1967)
7. Craniofacial syndromes such as clefts
8. Xerostomia determined from clinical history of the patient
9. Severely rotated teeth (limiting the appearance of buccal surfaces)
10. Heavy smokers determined by accounting the number of cigarettes per day and time to the first cigarette of the day (Heatherton et al., 1989) .

Locations

Location

Status

Recruiting