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A Study Comparing Tretinoin Cream 0.025% and RETIN-A® Cream 0.025% in the Treatment of Acne Vulgaris

Sponsored by Taro Pharmaceuticals USA

About this trial

Last updated 4 years ago

Study ID

TRTC-1912

Status

Completed

Type

Interventional

Phase

Early Phase 1

Placebo

No

Accepting

18-75 Years
12 to 40 Years
All
All

Trial Timing

Ended 5 years ago

What is this trial about?

The bioequivalence and safety of Tretinoin Cream 0.025% (Taro Pharmaceuticals U.S.A, Inc.) and RETIN-A® (Tretinoin) Cream 0.025% in the treatment of acne vulgaris.

What are the participation requirements?

Yes

Inclusion Criteria

- Healthy male or non-pregnant female aged ≥ 12 and ≤ 40 years with a clinical diagnosis of acne vulgaris.

- Subjects who are 18 years of age or older (up to the age of 40) must have provided IRB approved written informed consent. Subjects 12 to 17 years of age, inclusive, must have provided IRB approved written assent

- Subjects must have a definite clinical diagnosis of acne vulgaris severity grade 2, 3, or 4 as per the Investigator's Global Assessment (IGA)

No

Exclusion Criteria

- Female Subjects who are pregnant, nursing or planning to become pregnant during study participation

- Subjects with a history of hypersensitivity or allergy to tretinoin, retinoids, or any of the study medication ingredients.

- Subjects with the presence of any skin condition that would interfere with the diagnosis or assessment of acne vulgaris (e.g., on the face: rosacea, dermatitis, psoriasis, squamous cell carcinoma, eczema, acneiform eruptions caused by medications, steroid acne, steroid folliculitis, or bacterial folliculitis).

Locations

Location

Status