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Lichen Planus, Oral
+1

Treatment Protocols for Patients With Symptomatic Oral Lichen Planus

Sponsored by University of Messina

About this trial

Last updated 4 years ago

Study ID

121/120/PO

Status

Completed

Type

Interventional

Phase

N/A

Placebo

No

Accepting

18-75 Years
25 to 70 Years
All
All

Trial Timing

Ended 5 years ago

What is this trial about?

The primary objective of this study was to compare the therapeutic efficacy of clobetasol propionate 0.05% oral gel versus an anti-inflammatory mouthwash in an oral solution for the management of patients suffering from symptomatic OLP. The secondary objective was to analyze which one of the two treatments induced a greater risk of developing side effects.

What are the participation requirements?

Yes

Inclusion Criteria

- age ≥ 18 years;

- clinical diagnosis and histological diagnosis of OLP on the basis of WHO criteria;

- presence of symptoms related to OLP.

No

Exclusion Criteria

- presence of systemic conditions that may have affected the study results;

- state of pregnancy or breastfeeding;

- histological signs of dysplasia;

- drugs inducing a lichen response (ACE-inhibitors, β-blockers, etc.);

- treatment of OLP in the six months prior to the start of the programme;

- presence of extraoral lesions (genital, skin and other)

- history of previous immunodeficiency or HIV seropositivity;

- previous allogeneic bone marrow transplantation;

- presence of systemic lupus erythematosus or other autoimmune diseases.

Locations

Location

Status