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Misoprostol With or Without Letrozole in Treatment of Missed Miscarriage

Sponsored by Dr.Dalia Mohammed Al Sayed Zaki

About this trial

Last updated 5 years ago

Study ID

Treatment of missedmiscarriage

Status

Unknown status

Type

Observational

Placebo

No

Accepting

18-75 Years
18 to 35 Years
Female
Female

Trial Timing

Ended 5 years ago

What is this trial about?

Aim of study Compare the success rate of misoprostol with versus without letrozole as a pretreatment for medical termination of pregnancy during the first trimester. Hypothesis: Letrozole value as a pre-treatment medication for misoprostol in induction of abortion during the first trimester. Research question: Will letrozole- misoprostol protocol give better results than misoprostol- alone protocol in induction of abortion during the first trimester?

What are the participation requirements?

Yes

Inclusion Criteria

- Woman age more than 18 years old (age of legal consent).

- BMI ranges between 25 kg/m2 and 35 kg/m2.

- Gestational age of 63 days' gestation (or less).

- Missed abortion.

- Hemoglobin leve

No

Exclusion Criteria

- Woman age less than 18 years old.

- BMI less than 25 kg/m2 or more than 35 kg/m2.

- Gestational age more than 63 days' gestation.

- Molar pregnancy.

- Hemoglobin level less than 10 gm/dL.

- Fibroid uterus.

- Uterus with congenital anomalies.

- Previous attempts for induction of abortion in the current pregnancy.

- Coagulation defect i.e. coagulopathy.

- Contraindication for induction of abortion e.g. heart failure.

- Allergy to misoprostol or letrozole.

Locations

Location

Status