About this trial
Last updated 2 years ago
Study ID
Version: 1 [01-JUL-2019]
Status
Completed
Type
Observational
Placebo
No
Accepting
18+ Years
All
Trial Timing
Ended 2 years ago
What is this trial about?
The primary objective of this study is to assess stiffness, muscle tone, relaxation periods
and elasticity of various muscles in patients with dystrophic or non-dystrophic myotonia. The
secondary objectives are (1) to provide reference values for stiffness, muscle tone,
relaxation periods and elasticity of various muscles in patients with dystrophic or
non-dystrophic myotonia; to provide reference values for stiffness, muscle tone, relaxation
periods and elasticity of various muscles in patients with non-myotonic neuromuscular
disorders, (3) assess correlations between to compare result values for stiffness, muscle
tone, relaxation periods and elasticity with clinical muscle function tests, measured by
clinical evaluation (MRC-scale) and the 6-minute walk test; (4) assess correlations between
subcutaneous fat and muscle thickness and echogenicity, measured by muscle ultrasound and
result values for stiffness, muscle tone, relaxation periods and elasticity.
What are the participation requirements?
Inclusion Criteria
- ≥18 years of age
- Confirmed neuromuscular disease
- written consent
- able and willing to perform study prodcedures For healthy volunteers:
- age ≥18 years of age
- written informed consent
- no clinical sign for neuromuscular disorders
Exclusion Criteria
- Severe comorbidities
- Patient is participating in another clinical study using investigational treatment
- Patient cannot perform required muscle function tests
- the patient, in the opinion of the investigator, is unable to adhere to the requirements of the study