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Feasibility Study of the AffloVest in Bronchiectasis

Sponsored by Papworth Hospital NHS Foundation Trust

About this trial

Last updated 2 years ago

Study ID

PO2552

Status

Suspended

Type

Interventional

Phase

N/A

Placebo

No

Accepting

18-75 Years
18+ Years
All
All

Not accepting

Not accepting
Healthy Volunteers

Trial Timing

Ended 2 years ago

What is this trial about?

Feasibility study of High Frequency Chest Wall Oscillation (HFCWO) using the AffloVest in 30 patients with Bronchiectasis over a 6 week period. Outcome measures include lung function, quality of life questionnaire, High resolution computed Tomography and visual analogue scale for ease of clearance.

What are the participation requirements?

Yes

Inclusion Criteria

- Adult male and females 18 years or over

- Current diagnosis of bronchiectasis

- Productive of sputum on a daily basis

- Clinical stability over a 2 week period prior to enrolment

No

Exclusion Criteria

- Cystic fibrosis

- Severe obstructive airways disease (defined as FEV1 less than 25 percent)

- Predominant lung disease is not bronchiectasis in the opinion of the investigator (e.g. asthma, Chronic Obstructive Pulmonary Disease (COPD), pulmonary fibrosis)

- Bronchiectasis in only 1 lobe

- Currently treated non-tuberculous mycobacterial lung disease

- Acute congestive cardiac failure

- Contra-indication or unable to perform HRCT imaging, including pregnancy

- Contra-indication to using AffloVest including lung malignancy, recent rib fractures, radiological evidence of lung cavitation, and recent significant haemoptysis (in the opinion of the investigator)

- History of poor adherence to physiotherapy treatment

- Cognitive or memory problems affecting ability to follow instructions or give informed consent

Locations

Location

Status