Identification of Biomarkers in Ischemic Stroke - Clinical Trial
Sponsored by University Hospital, Brest
About this trial
Last updated 2 years ago
Study ID
Status
Type
Phase
Placebo
Accepting
Trial Timing
Ended a year ago
What is this trial about?
What are the participation requirements?
Inclusion Criteria
- For ischemic stroke :
- Age > 18-year-old
- Ischemic stroke diagnosed on clinical presentation and cerebral imaging (CT or MRI imaging)
- Inclusion inferior to 6 hours from stroke onset
- Initial NIHSS score > 0 at the time of clinical examination
- Patients with multimodal imaging either through MRI or CT perfusion and supra-aortic vessels and intra-cerebral vessels (Willis circle) imaging <0
- Procedure of signed consent in situation of emergency : consent of the patient if he has the possibility to sign or his representative if he is present
- For hemorragic stroke :
- Age > 18 year-old
- Hemorrhagic stroke diagnosed on clinical presentation and cerebral imaging (CT or MRI imaging)
- Inclusion inferior to 6 hours from stroke onset
- Initial NIHSS score > 0 at the time of clinical examination
- Hemorrhagic patients are paired for age and sex with ischemic patients
- Procedure of signed consent in situation of emergency : consent of the patient if he has the possibility to sign or his representative if he is present For healthy controls :
- Age > 18 year-old
- Stroke-free standardized questionnaire
- Initial NIHSS score = 0
- Rankin score = 0
- High risk cardiovascular subjects
- Controls are paired for age, sex and cardiovascular risk measured by a score (European Heart Score) with ischemic patients
Exclusion Criteria
- Not affiliated to social security
- Patient under legal protection or deprived of liberty by a judicial or administrative decision
- Patient whose follow-up will be impossible
- Prior stroke GROUP FOR ISCHEMIC STROKE :
- Patients with TIA and a negative cerebral CT or MRI GROUP FOR HEMORRAGIC STROKE :
- Contraindication MRI