The investigator measured the arterial stiffness using cardio-ankle vascular index (CAVI)
test in patient with preeclampsia and normal pregnant women to evaluate the longitudinal
change of CAVI and their predictors.

Comparison of Longitudinal Blood Pressure and Arterial Stiffness in Preeclamptic Women After Delivery

Preeclampsia and Eclampsia

Stiffness, Aortic

Blood Pressure

This study was a case control study and included 37 women with preeclampsia (PE group)
and 36 normotensive women (control group) who gave birth to child at Seoul National
University Bundang Hospital.

Cario-ankle vasuclar index (CAVI) was measured at one day, six months and one year after
delivery in both group.

The investigator also checked the body weight, blood pressure, lipid profile, serum
creatinine, aspartate transaminase (AST) and alanine transaminase (ALT) simultaneously
with CAVI.

The relationship between the presence of preelampsia and longitudinal changes of CAVI,
blood pressure and metabolic indices were evaluated using generalized estimating equation
(GEE) method.

Comparison of Longitudinal Blood Pressure and Arterial Stiffness in Preeclamptic and Normotensive Women After Delivery: One-Year Follow-Up Results

The CAVI was analyzed with generalized estimating equation (GEE) method to evaluate the
different change pattern of CAVI between two groups.

Principal investigator

Waist circumference in centimeter, Hip circumference in centimeter, Waist/Hip
Circumference Ratio is the ratio of waist circumference divided by hip circumference

PE was defined as diastolic BP of at least 110 mmHg on one occasion or diastolic BP of at
least 90 mmHg on two consecutive occasions more than 4 hours apart, in combination with
proteinuria (≥300 mg total protein in a 24-hour urine collection and, if this was not
available, ≥+2 proteinuria by dipstick analysis on two consecutive occasions at least 4
hours apart) that develops after 20 weeks of gestation in previously normotensive women

Comparison of Longitudinal Blood Pressure and Arterial Stiffness in Preeclamptic Women After Delivery

About this trial

Study ID

Status

Type

Placebo

Accepting

Trial Timing

What is this trial about?

What are the participation requirements?

Locations

Location

Status