Effects of intranasal oxytocin (24IU) on cognitive control of attention

Oxytocin Effect on Attention Inhibition

Healthy

The cognitive control of attention towards neutral and emotional stimuli represents a key
      functional domain and disruptions in this domain have been associated with a range of
      psychiatric disorders. Saccadic eye movement tasks have been used to assess individual
      differences in the cognitive control of attention and alterations in psychiatric disorders.
      Recent evidence suggests that the hypothalamic neuropeptide Oxytocin (OXT) may modulate
      attention allocation and regulation. To this end the present randomized between-subject
      placebo-controlled experiment examined whether intranasal OXT modulates behavior in an
      eye-tracking saccade / anti-saccade paradigm in healthy male subjects. The paradigm used
      non-social (neutral shape) as well as social (happy, sad, angry, fear, and neutral faces)
      stimuli to explore emotion-specific effects of OXT.

oxytocin treatment

placebo treatment

An Eye-tracking Study to Investigate Oxytocin Effect on Attention Inhibition

comparison between emotion-specific saccade latencies between the treatment groups (in milliseconds)

comparison between the emotion-specific ratio of unsuccessful anti-saccades between the treatment groups.

Oxytocin Effect on Attention Inhibition

About this trial

Study ID

Status

Type

Phase

Placebo

Accepting

Trial Timing

What is this trial about?

What are the participation requirements?