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Xylometazoline During Nasal Flexible Bronchoscopy

Sponsored by All India Institute of Medical Sciences

About this trial

Last updated 7 years ago

Study ID

IEC AIIMS/Vasoconstrictor RCT

Status

Completed

Type

Interventional

Phase

N/A

Placebo

No

Accepting

18+ Years
All Sexes

Trial Timing

Ended 7 years ago

What is this trial about?

Flexible bronchoscopy is a commonly performed procedure and is usually performed transnasally. The optimal topical anesthesia regimen for bronchoscopy is investigational. Topical Vasoconstrictors like xylometazoline produce decongestion of nasal mucosa and may make insertion of bronchoscope easier. The addition of topical vasoconstrictor to lignocaine may have advantage in terms of patient comfort and for reducing local complications. Although evaluated in the settings of nasal endoscopy and nasotracheal intubation, randomized trials on the role of topical vasoconstrictors during flexible bronchoscopy are not available. The aim of this randomized trial is to study the effect of topical nasal xylometazoline administration during flexible bronchoscopy.

What are the participation requirements?

Inclusion Criteria

- All adults > 18 years of age undergoing flexible bronchoscopy via nasal route

Exclusion Criteria

* Uncontrolled hypertension

* coronary artery disease

* Pregnancy

* refusal of consent

* Hypoxemia (oxygen saturation [by pulse oximetry] < 92% with Fio2 of ≥ 0.3

* Bronchoscopy not performed by nasal route

* Bronchoscopy performed through an artificial airway