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Cirrhosis
+3

Modified Vagus Nerve-preserving Laparoscopic Splenectomy and Azygoportal Disconnection

Sponsored by Yangzhou University

About this trial

Last updated 5 years ago

Study ID

YZUC-003

Status

Completed

Type

Interventional

Phase

N/A

Placebo

No

Accepting

18-75 Years
18 to 75 Years
All
All

Not accepting

Not accepting
Healthy Volunteers

Trial Timing

Ended 5 years ago

What is this trial about?

This study aimed to evaluate whether vagus nerve-preserving laparoscopic splenectomy and azygoportal disconnection is effective and safe, and to determine whether a reduction in the incidence of postoperative complications of the digestive system improves postoperative quality of life compared with conventional laparoscopic splenectomy and azygoportal disconnection.

What are the participation requirements?

Yes

Inclusion Criteria

- A clinical, radiological or histologic diagnosis of cirrhosis of any etiology

- Splenomegaly with secondary hypersplenism

- Bleeding portal hypertension

- No evidence of portal vein system thrombosis by ultrasound evaluation and angio-CT

- Informed consent to participate in the study

No

Exclusion Criteria

- Delayed gastric emptying

- Diarrhea

- Hepatocellular carcinoma or any other malignancy,

- Hypercoagulable state other than the liver disease related

- DRUGS- oral contraceptives, anticoagulation or anti-platelet drugs.

- Child - Pugh C

- Recent peptic ulcer disease

- History of Hemorrhagic stroke

- Pregnancy.

- Uncontrolled Hypertension

- Age>75 yrs

- Human immunodeficiency virus (HIV) infection