Influence of the Immunosystem in Non-celiac Glutensensitivity
Sponsored by University of Erlangen-Nürnberg Medical School
About this trial
Last updated 2 years ago
Study ID
Glutensensitivity
Status
Completed
Type
Interventional
Phase
N/A
Placebo
No
Accepting
18+ Years
All Sexes
Trial Timing
Ended 10 years ago
What is this trial about?
Patients with non-celiac gluten sensitivity (NCGS) complain about gastrointestinal and extraintestinal symptoms while consuming gluten-containing cereals. The symptoms strictly correlate with ingestion of gluten-containing cereals and disappear quickly under elimination diets. Till now, there are no specific markers to diagnose NCGS. This study aims to determine the effect of a low FODMAP diet (fermentable oligo-, di- and monosaccharides and polyols) and a glutenfree diet on the mucosal immunity, clinical symptoms, and psychological well-being. Furthermore, the influence of the diets on the microbiome will be analyzed.
What are the participation requirements?
Inclusion Criteria
* healthy controls
* patients with glutensensitivity
Exclusion Criteria
* patients with glutensensitivity but without celiac disease or wheat allergy