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Analgesia in Inguinal Hernia Repair Using a Cyclooxygenase-2-specific Inhibitor

Sponsored by Bnai Zion Medical Center

About this trial

Last updated 10 years ago

Study ID

BnaiZionMC-16-LG-009

Status

Completed

Type

Interventional

Phase

N/A

Placebo

Yes

Accepting

18 to 65 Years
All Sexes

Trial Timing

Ended 10 years ago

What is this trial about?

Acute pain is the result of activating nociceptive pathways in both the peripheral and central nervous system. The origin of most acute pain from surgical stimulation is the mechanical trauma of the local tissue and the subsequent acute inflammatory response. No studies have investigated the combined use of anti-inflammatory analgesics with spinal anaesthesia/analgesia for pre, intra and postoperative multimodal pain protection in patients undergoing day-case IHR. The aim of the investigators study is therefore to assess the efficacy of preoperative combined administration of etoricoxib and standard spinal anaesthesia in the reduction of postoperative pain following IHR.

What are the participation requirements?

Inclusion Criteria

* American Society Anesthesiology Class I and II

Exclusion Criteria

* Under treatment with Non Steroid Antinflammatory Drug

* Under Opioid treatment

* Peptic ulcer

* Liver insufficiency

* Renal insufficiency

* Asthma

* Cardiovascular disease