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Wrinkles
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Assessment of the Impact of a Coenzyme Q10 Supplementation on the Skin

Sponsored by VIST - Faculty of Applied Sciences

About this trial

Last updated 4 years ago

Study ID

Q10 01-2014

Status

Completed

Type

Interventional

Phase

N/A

Placebo

No

Accepting

18-75 Years
45 to 60 Years
Female
Female

Trial Timing

Ended 10 years ago

What is this trial about?

Objective of the study is to determine the influence of dietary supplementation with coenzyme Q10 (CoQ10) on skin conditions. 33 healthy female subjects will be randomly assigned to a placebo group, a low-dose (LD) group receiving 50 mg CoQ10/day and a high-dose group (HD) receiving 150 mg CoQ10/day (11 subjects per group). A water-soluble form of CoQ10 with improved bioavailability (Quvital syrup with Q10vital®, Valens Int. d.o.o., Slovenia) will be used. Various skin parameters will be evaluated before the supplementation (the baseline), after 6 and after 12 weeks of supplementation. To evaluate the photoprotective potential of CoQ10 the minimal erythema dose (MED) will be determined before (the baseline) and after 12 weeks of the supplementation.

What are the participation requirements?

Yes

Inclusion Criteria

- Signs of skin aging (mimic wrinkles/ poor skin tone/ visual dryness),

- Photoaged skin on the face,

- Expression of mimic wrinkles,

- Phototype II and III.

No

Exclusion Criteria

- Allergy to ingredients of tested products

- High blood cholesterol and use of cholesterol-lowering medicines,

- Diagnosed diabetes

- Thyroid disease

- Inflammatory skin diseases,

- Regular use of dietary supplements 6 months or less before start of the study,

- Invasive rejuvenation treatments (botox injections, hyaluronic acid fillers, needle rollers, needle mesotherapy, etc.) 6 months or less prior to start of the study,

- Non-invasive rejuvenation treatments (radiofrequency, electrotherapy, ultrasound therapy, no-needle mesotherapy, etc.) 6 months or less prior to start of the study,

- The use of cosmetic products containing coenzyme Q10 6 months or less prior to start of the study,

- Gluteal hyperpigmentation,

- Expected sunbathing (also in solariums) within the study period.