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Myometrial Thickness as a Predictor for the Latency Interval in PPROM

Sponsored by Cairo University

About this trial

Last updated 8 years ago

Study ID

129

Status

Unknown

Type

Observational

Placebo

No

Accepting

18 to 40 Years
Female

Trial Timing

Ended 7 years ago

What is this trial about?

100 women divided into 3 groups: * Group I: included 50 women with preterm premature rupture of membranes (PPROM, n=50) with gestational age from 24 to 34 weeks. * Group II: included 25 term non-labor control (T-CTR, n=25) with gestational age from 37 to 41 weeks. * Group III: included 25 preterm non-labor control (P-CTR, n=25) with gestational age from 24 to 34 weeks.The myometrial thickness at 4 different sites9: a) The lower uterine segment (LUS): 2cm above the reflection of the full urinary bladder (b)The anterior wall: 1cm above the maternal umbilicus. (c)Fundus: by placing the scan probe perpendicularly above the uterine fundus so that the entire curvature of the uterus was visualized. (d)The posterior wall: through using the maternal abdominal aortic pulsation as an anatomic marker. At least 3 measurements were obtained at each site and averaged. The latency interval is determined in each of the 3 groups.

What are the participation requirements?

Inclusion Criteria

* singleton pregnancy with a definite history of current PPROM for the study group

Exclusion Criteria

* Suspected fetal growth restriction (IUGR),

* Any gross fetal anomalies,

* Abnormalities of placentation,

* Uterine structural abnormalities,

* Fetal jeopardy or intrauterine fetal death (IUFD).

* Women presenting with chorioamniointis with fever over 38 c abdominal tenderness, foul vaginal discharge and/or fetal tachycardia.

* Diabetics, immunocompromized and cardiac patients.

* Women with cervical cerclage.

* Women with drained liquor