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Infertility
+1

Single Embryo TrAnsfeR of Euploid Embryo

Sponsored by Illumina, Inc.

About this trial

Last updated 5 years ago

Study ID

RGH-001

Status

Completed

Type

Interventional

Phase

N/A

Placebo

No

Accepting

18-75 Years
25 to 40 Years
Female
Female

Not accepting

Not accepting
Healthy Volunteers

Trial Timing

Ended 9 years ago

What is this trial about?

The purpose of the current study is to evaluate the effect of preimplantation genetic screening (PGS) by next generation sequencing (NGS) compared to standard morphological assessment of embryos on pregnancy rates through a randomized controlled trial (RCT). All embryos will be vitrified and a single embryo transfer (SET) will be performed with either screened or unscreened embryos depending on randomization.

What are the participation requirements?

Yes

Inclusion Criteria

- Patient undergoing IVF

- At least 2 blastocysts suitable for biopsy on day 5 or 6 of embryo development

No

Exclusion Criteria

- History of more than two prior implantation failure following IVF

- History of more than one miscarriage of viable pregnancy

- One or both partners known to be carrier(s) of a chromosomal abnormality

- Known genetic carrier couple and/or one or both partners carrier of a known autosomal dominant disorder

- Any other non-study related preimplantation genetic testing

- Use of donor oocytes

- Use of gestational carrier (surrogate or donor egg recipient).

- Severe oligospermia (<1,000,000 sperm/ml); Surgical Sperm Retrieval for reasons other than post-vasectomy and CAVD

- Low ovarian reserve with (FSH) >10 IU/L on day 2-4 of a prior menstrual cycle and/or (AMH) <7 pmol/L (or <1 ng/ml)

- Gender selection cycles

- Concurrent participation in another clinical trial

Locations

Location

Status