CDX_000021

About this trial

Last updated 6 years ago

Study ID

CDX_000021

Status

Withdrawn

Type

Observational

Placebo

Accepting

21+ Years

All

Not accepting

Healthy Volunteers

Trial Timing

Ended 10 years ago

This retrospective study will investigate clinician behavior in diagnosing patients with possible obstructive coronary artery disease who received a Corus CAD (Age/Sex/Gene Expression score - ASGES) result compared to patients who did not have the test performed (matched control patients).

Inclusion Criteria

- Symptoms suggestive of obstructive CAD, according to the opinion of the site clinician

- Age >= 21 years

- Resulted Corus CAD (ASGES) test used during the evaluation and/or diagnosis of symptoms suggestive of obstructive coronary artery disease (CAD), preferably 1 year prior to data collection date. For Control arm:

- Symptoms suggestive of obstructive CAD, according to the opinion of the site clinician

- Eligible for Corus CAD (ASGES) (see exclusion criteria)

- Matched to Corus CAD (ASGES) patients by sex, age +/-2.5 years, and presenting symptoms

Exclusion Criteria

- History of myocardial infarction (MI) or CAD prior to the index evaluation

- Presentation of high risk unstable angina for the index evaluation

- Concurrent systemic infection or inflammatory process

- Concurrent MI or acute coronary syndrome

- Known diabetes mellitus diagnosis or laboratory test results suggestive of a diagnosis of diabetes mellitus (e.g., HbA1C >=6.5)

- Use of steroids, immunosuppressive agents, or chemotherapeutic agents, at time of chest pain presentation

Clinician Utilization of Corus CAD (or ASGES) in Primary Care Provider Decision Making