SSaSS

About this trial

Last updated 4 years ago

Study ID

SSaSS

Status

Completed

Type

Interventional

Phase

N/A

Placebo

Accepting

All

Not accepting

Healthy Volunteers

Trial Timing

Ended 5 years ago

The study is a large scale cluster randomised trial to evaluate the effects of sodium reduction based upon the use of salt substitute on the risk of stroke defined as the occurrence of stroke and stroke deaths. The corresponding null hypothesis that will be tested is that sodium reduction will have no effect upon stroke risk. The secondary objectives are to determine effects of sodium reduction on major vascular events and total mortality.

Inclusion Criteria

- Disease history

- Prior stroke and/or

- Aged 60 years or over and with uncontrolled high blood pressure (systolic blood pressure >=140 millimeters of mercury (mmHg) at visit if on blood pressure lowering medication; systolic blood pressure>=160 millimeters of mercury (mmHg) if not on blood pressure lowering medication)

- Ownership of a phone by the participant or a household member

Exclusion Criteria

- Participant or family member is using a potassium-sparing diuretic

- Participant or family member is using a potassium supplement

- Participant or family member has serious renal impairment

- Participant or family member has other reason for concern about use of salt substitute

- Participant eats most meals outside the home

- Participant is not expected to live longer than 6 months from the date of assessment as estimated by the village doctor

- Another family member living in the same household has already been included in the study

China Salt Substitute and Stroke Study