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Study of Betatrophin Levels in Patients With Type 2 Diabetes and Gestational Diabetes and Healthy Subjects

Sponsored by Qingdao University

About this trial

Last updated 11 years ago

Study ID

Betatrophin-Human

Status

Unknown status

Type

Observational

Placebo

No

Accepting

18-75 Years
20+ Years
All
All

Not accepting

Not accepting
Healthy Volunteers

Trial Timing

Ended 11 years ago

What is this trial about?

Betatrophin is a newly identified hormone that promotes pancreatic beta cell proliferation, improves glucose tolerance and regulates lipids metabolism. A recent study showed that circulating concentrations of betatrophin doubled in type 1 diabetes. The objective of this study is to investigate the association of serum betatrophin levels with the progression of diabetic retinopathy in patients with type 2 diabetes and the level of betatrophin in gestational diabetes patients and pregnant women.

What are the participation requirements?

Yes

Inclusion Criteria

- Type 2 diabetes mellitus patients

- Patients with HbA1c >or= 7.0%

No

Exclusion Criteria

- Participation in other investigational Clinical Trial

- Type 1 diabetes mellitus patients

- Patients with history of severe hepatic dysfunction

- Treatment with antifungal agent especially Miconazole

- Patients with active smoking or history of smoking cessation less than 2 months