Local injection of 5-fluorouracil into a chalazion (stye) is as effective as local
injection of triamcinolone (steroid) and incision and curettage for treatment of
chalazia.

Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study

Chalazion

This is a prospective randomized interventional study comparing four current
standard-of-care treatments for chalazia: incision and curettage, local injection of
triamcinolone, local injection of 5-FU, and local injection of combination
triamcinolone/5-FU.

5-fluorouracil Injection

Triamcinolone Acetonide

Incision and Curettage

Triamcinolone Acetonide/5-fluorouracil mixture

Assistant Professor of Ophthalmology

A vertical incision over the area of chalazion will be done. Inflammatory material will
be removed and the chalazion capsule will be excised.

0.1 ml of triamcinolone is injected directly in the chalazion.

0.1 ml of 5-fluorouracil is injected directly in the lesion transconjunctivally.

0.1 ml of a 4:1 mixture of 4 parts 5-FU and 1 part triamcinolone is injected in the
lesion.

Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study

About this trial

Study ID

Status

Type

Phase

Placebo

Accepting

Not accepting

Trial Timing

What is this trial about?

What are the participation requirements?

Locations

Location

Status