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Diurnal and Nocturnal Effect of Travatan With SofZia Preservative on Intraocular Pressure and Ocular Perfusion Pressure

Sponsored by University of Colorado, Denver

About this trial

Last updated 10 years ago

Study ID

12-0175

Status

Completed

Type

Observational

Placebo

No

Accepting

18 to 90 Years
All Sexes

Trial Timing

Ended 13 years ago

What is this trial about?

The purpose of this research study is to determine the diurnal and nocturnal effects of Travoprost with SofZia (Travatan Z) on intraocular pressure and ocular perfusion pressure.

What are the participation requirements?

Inclusion Criteria

* Diagnosis of open-angle glaucoma or ocular hypertension, including pigment dispersion glaucoma and pseudoexfoliation glaucoma

* Age ≥ 18 or ≤ 90 years, of either gender, or any race/ethnicity

Exclusion Criteria

* Females who are currently pregnant or planning to become pregnant, as determined by history during the study period

* Diagnosis of any other form of glaucoma other than open-angle

* Schaffer angle grade < 2 in either eye by gonioscopy

* Chronic, recurrent, or severe inflammatory eye disease

* Intraocular surgery within 6 months or laser within 3 months

* History of active, recurrent, or chronic ocular infection with the Herpes Simplex Virus

* History of cystoid macular edema

* Inability to safely discontinue all ocular medications for 4 weeks

* Patients who smoke or have irregular daily sleep patterns

* Patients who have started or changed glucocorticoids therapy in the last 3 months

* Patients who are currently undergoing medical marijuana therapy

* Any use of a non-FDA approved medication for glaucoma in the last 3 months