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A Study to Evaluate the Efficacy and Safety of ALKS 9072 (Also Known as Aripiprazole Lauroxil, ALKS 9070, or ARISTADA) in Subjects With Schizophrenia

Sponsored by Alkermes, Inc.

About this trial

Last updated 6 years ago

Study ID

ALK9072-003

Status

Completed

Type

Interventional

Phase

Phase 3

Placebo

Yes

Accepting

18-75 Years
18 to 70 Years
All
All

Not accepting

Not accepting
Healthy Volunteers

Trial Timing

Ended 11 years ago

What is this trial about?

The study will determine the efficacy of ALKS 9072 (also known as aripiprazole lauroxil or ALKS 9070) for the treatment of schizophrenia in subjects experiencing an acute exacerbation.

What are the participation requirements?

Yes

Inclusion Criteria

- Diagnosis of schizophrenia according to DSM-IV-TR criteria - Has been able to achieve outpatient status for more than 3 months in the past year - Body mass index (BMI) of 18.5 to 40.0 kg/m2 (inclusive) - Resides in a stable living situation - Willing and able to be confined to an inpatient study unit for 2 weeks or longer

No

Exclusion Criteria

- History of poor or inadequate clinical response to treatment with aripiprazole - History of treatment resistance - Known or suspected intolerance of, allergy, or hypersensitivity to aripiprazole, its ingredients, other antipsychotic agent, or INTRALIPID (including peanuts, soy, egg, or glycerol) - Diagnosis of current substance dependence (including alcohol) - Pregnant, lactating, or breastfeeding - Receipt of any antipsychotic medication by IM injection within 60 days before Screening - Current involuntary hospitalization or incarceration - Hospitalized for more than 30 days during the 90 days before Screening Additional inclusion/exclusion criteria may apply.

Locations

Location

Status