The purpose of this study is to determine whether subjects taking a supplement designed
to increase metabolic rate will have a positive effect on body composition (fat mass,
muscle mass, and bone density.)

A Comparative Effectiveness Study Evaluating the Effects of Thermogenic Supplements on Body Composition

Weight Loss

In a previous randomized double-blinded placebo-controlled pilot study, subjects taking
the nutritional supplements contained in these two weight loss plans had a short-term
statistically significant increase in their resting metabolic rates as compared to taking
a placebo. No increases were found in blood pressure, resting heart rate, or
self-reported discomfort when taking the supplement.

The current study was designed to extend the findings of the pilot study over a 60-day
study period using a randomized double-blinded placebo-controlled protocol with the same
weight loss interventions.

Advantra Z

Advantra Z + Naringin + Hesperiden

Sugar pill

A Comparative Effectiveness Study Evaluating the Effects of Two Thermogenic Supplements on Body Composition Using a Double-Blinded Placebo-Controlled Protocol

This study goes beyond assessing changes in scale weight and BMI. DXA is used to assess
changes in body composition (lean, fat and bone) associated with the weight loss
interventions.

Dr. Gilbert R. Kaats, PhD

43 chemistries including Lipids, CBC, Metabolic panel, TSH, and Cardio CrP

Measures the amount of force (pressure) that blood exerts on the walls of the blood
vessels as it passes through them. Systolic blood pressure is a measure of blood pressure
while the heart is beating. Diastolic pressure is a measure of blood pressure while the
heart is relaxed, between heartbeats. Measurements will be taken after sitting or lying
down for at least 5 minutes. Changes will be reported between baseline and day 30 of
study.

Measure of heart rate after sitting or lying down for at least 5 minutes. Changes will be
reported between baseline and day 30 of study.

Measure of heart rate after sitting or lying down for at least 5 minutes. Changes will be
reported between day 30 and 60 of study.

Measures the amount of force (pressure) that blood exerts on the walls of the blood
vessels as it passes through them. Systolic blood pressure is a measure of blood pressure
while the heart is beating. Diastolic pressure is a measure of blood pressure while the
heart is relaxed, between heartbeats. Measurements will be taken after sitting or lying
down for at least 5 minutes. Changes will be reported between baseline and day 60 of
study.

Measure of heart rate after sitting or lying down for at least 5 minutes. Changes will be
reported between baseline and day 60 of study.

A subscale of the 86-item quality of life inventory assessing 15 items related to the
subjects' ability to control eating behavior

Measures the amount of force (pressure) that blood exerts on the walls of the blood
vessels as it passes through them. Systolic blood pressure is a measure of blood pressure
while the heart is beating. Diastolic pressure is a measure of blood pressure while the
heart is relaxed, between heartbeats. Measurements will be taken after sitting or lying
down for at least 5 minutes. Changes will be reported between mid-point and day 60 of
study.

Participants will have opportunity to report on a daily basis any adverse events
experienced.

Proprietary ingredient for: stimulating thermogenesis, reducing weight, increasing lean
muscle mass to total body mass, improving athletic performance, and suppressing appetite

A Comparative Effectiveness Study Evaluating the Effects of Thermogenic Supplements on Body Composition

About this trial

Study ID

Status

Type

Phase

Placebo

Accepting

Trial Timing

What is this trial about?

What are the participation requirements?

Locations

Location

Status