This website uses cookies to enhance your browsing experience, improve site performance, and gather analytics. By selecting 'Accept,' you consent to these cookies as described in our Privacy Policy.

Logo
Depression

Effectiveness of Theta-burst Stimulation (TBS) in Patients With Major Depression

Sponsored by University of Regensburg

About this trial

Last updated 13 years ago

Study ID

Uni-Reg-TB1

Status

Completed

Type

Interventional

Phase

N/A

Placebo

No

Accepting

18 to 70 Years
All Sexes

Not accepting

Healthy Volunteers

Trial Timing

Ended 15 years ago

What is this trial about?

Repetitive Transcranial Magnetic Stimulation (rTMS) as well as Theta- Burst Stimulation of the frontal cortex are used to modulate the neuronal excitability in patients with depression. In the proposed study we investigate whether high frequent rTMS or Theta-Burst Stimulation of the DLPFC is more effective in patients with a depressive episode.

What are the participation requirements?

Inclusion Criteria

* Episode of depression (unipolar or bipolar)( ICD-10)

* Female or male between 18 and 70 years

* Skills to participate in all study procedures

* 18 or more points in the Hamiliton rating scale or depression

* Stable antidepressant drugs

* Written informed consent

Exclusion Criteria

* Clinically relevant unstable internal or neurological comorbidity

* Evidence of significant brain malformations or neoplasm, head injury

* Cerebral vascular events

* Neurodegenerative disorders affecting the brain or prior brain surgery

* Metal objects in and around body that can not be removed

* Pregnancy

* Alcohol or drug abuse

* Epilepsy or a pathological EEG

* Heart pacemaker

* High dose tranquillizers